2-((叔丁氧基羰基)氨基)-3-甲氧基-3-氧代丙酸合成路线 （共 4 条）
反应条件
sodium hydroxide in 1,4-dioxane
15 h; Ambient temperature;
参考文献
Schmidt; Leitenberger; Griesser; Meyer
Synthesis, 1992 , # 12 p. 1248 - 1254
反应条件
1: KHCO3 / H2O; tetrahydrofuran; dioxane / 1.) 0 deg C, 2 h, 2.) room temperature
2: KOH / ethanol / 0 °C
View Scheme
参考文献
Krumme, Dirk; Tschesche, Harald
Tetrahedron, 1999 , vol. 55, # 10 p. 3007 - 3018
反应条件
1: diethyl ether
2: 1) nBuLi, (iPr)2NH, TMEDA / 1) THF, hexane, -78 deg C, 1 h, 2) THF, hexane, -78 deg C to RT
View Scheme
参考文献
Matt, Thomas; Seebach, Dieter
Helvetica Chimica Acta, 1998 , vol. 81, # 10 p. 1845 - 1895
反应条件
N,N,N',N,-tetramethylethylenediamine; lithium diisopropyl amide
1.) THF, -75 deg C; Yield given. Multistep reaction;
参考文献
Bossler, Hans G.; Waldmeier, Pius; Seebach, Dieter
Angewandte Chemie, 1994 , vol. 106, # 4 p. 455 - 456
