1: 2-chloro-quinoline With copper(l) iodide; triethylamine; triphenylphosphine; palladium on activated charcoal in water
T=25 - 30°C; 0.5 h;
2: hex-1-yne in water
T=20 - 80°C; Sonogashira coupling; Further stages.;
1: 2-chloro-quinoline With copper(l) iodide; triethylamine; triphenylphosphine; palladium on activated charcoal in water
T=25 - 30°C; 0.5 h;
2: propargyl alcohol in water
T=20 - 80°C; Sonogashira coupling; Further stages.;
Jones, Nicholas A.; Antoon, James W.; Bowie Jr., Alfred L.; Borak, J. Brian; Stevens, Erland P.
Journal of Heterocyclic Chemistry, 2007 , vol. 44, # 2 p. 363 - 367