3’-N,N-二(去甲基)阿奇霉素合成路线 （共 2 条）
反应条件
iodine; sodium methylate in methanol
T=0 - 20°C; 3 h;
参考文献
Jakopovic, Ivana Palej; Krajacic, Mirjana Bukvic; Skugor, Maja Matanovic; Stimac, Vlado; Pesic, Dijana; Vujasinovic, Ines; Alihodzic, Sulejman; Paljetak, Hana Cipcic; Kragol, Goran
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 10 p. 3527 - 3530
反应条件
1: N-iodo-succinimide / acetonitrile / 1.5 h
2: iodine; sodium methylate / methanol / 3 h / 0 - 20 °C
View Scheme
参考文献
Jakopovic, Ivana Palej; Krajacic, Mirjana Bukvic; Skugor, Maja Matanovic; Stimac, Vlado; Pesic, Dijana; Vujasinovic, Ines; Alihodzic, Sulejman; Paljetak, Hana Cipcic; Kragol, Goran
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 10 p. 3527 - 3530
