4-(1H-吡咯并[2,3-b]3-吡啶基)-1-哌啶羧酸乙酯合成路线 （共 4 条）
反应条件
hydrogen; palladium 10 on activated carbon in ethanol
P=1551.49 Torr; 24 h; Product distribution / selectivity;
参考文献
ALMIRALL PRODESFARMA S.A.; PRIETO SOTO, Jose, Manuel
Patent: WO2003/82867 A1, 2003 ;
Location in patent: Page/Page column 51 ;
WO 03/082867 A1
反应条件
triethylamine in dichloromethane
T=0°C; 6 h; Product distribution / selectivity;
参考文献
ALMIRALL PRODESFARMA S.A.; PRIETO SOTO, Jose, Manuel
Patent: WO2003/82867 A1, 2003 ;
Location in patent: Page/Page column 23 ;
WO 03/082867 A1
反应条件
1: KOH / methanol / 15 h / 60 °C
2: H2 / PtO2 / methanol / 1 h / 1551.44 Torr
View Scheme
参考文献
Fonquerna, Silvia; Miralpeix, Montse; Pages, Lluis; Puig, Carles; Cardus, Arantxa; Anton, Francisca; Vilella, Dolors; Aparici, Monica; Prieto, Jose; Warrellow, Graham; Beleta, Jorge; Ryder, Hamish
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 4 p. 1165 - 1167
反应条件
1: KOH / methanol / 15 h / 60 °C
2: H2 / PtO2 / methanol / 1 h / 1551.44 Torr
View Scheme
参考文献
Fonquerna, Silvia; Miralpeix, Montse; Pages, Lluis; Puig, Carles; Cardus, Arantxa; Anton, Francisca; Vilella, Dolors; Aparici, Monica; Prieto, Jose; Warrellow, Graham; Beleta, Jorge; Ryder, Hamish
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 4 p. 1165 - 1167
