N-[1-苄基哌啶-4-基]丙烷-1,3-二胺合成路线 （共 3 条）
反应条件
1: With sodium tetrahydroborate; cobalt(II) chloride in methanol
T=0°C; 2.25 h;
2: With hydrogenchloride in methanol; water
3: With sodium hydroxide in water
T=10°C; pH=12;
参考文献
SCHERING CORPORATION
Patent: EP1144402 B1, 2004 ;
Location in patent: Page 9; 10 ;
EP 1144402 B1
参考文献
Ciba-Geigy Corporation
Patent: US4329348 A1, 1982 ;
反应条件
in tetrahydrofuran
T=60°C; 14 h;
参考文献
SCHERING CORPORATION
Patent: EP1144402 B1, 2004 ;
Location in patent: Page 10 ;
EP 1144402 B1
