potassium carbonate in N,N-dimethyl-formamide; acetone 40 h; Heating;

1: 1.) BF3-etherate / 1.) DMF, to 60 deg C, 2.) a) r.t., b) boil. water bath, 3 h 2: K2CO3 / acetone / 36 h / Heating View Scheme

1: 2.6 g / KI/K2CO3 / acetone / 30 h / Heating 2: 2.2 g / 30percent H2O2/aq. NaOH / ethanol; acetone; H2O / Ambient temperature 3: BF3*OEt2 / benzene / 1 h 4: glacial acetic acid, conc. HCl / 2 h / Heating 5: 0.1 g / anhydrous K2CO3 / acetone; dimethylformamide / 40 h / Heating View Scheme

1: 2.2 g / 30percent H2O2/aq. NaOH / ethanol; acetone; H2O / Ambient temperature 2: BF3*OEt2 / benzene / 1 h 3: glacial acetic acid, conc. HCl / 2 h / Heating 4: 0.1 g / anhydrous K2CO3 / acetone; dimethylformamide / 40 h / Heating View Scheme

1: BF3*OEt2 / benzene / 1 h 2: glacial acetic acid, conc. HCl / 2 h / Heating 3: 0.1 g / anhydrous K2CO3 / acetone; dimethylformamide / 40 h / Heating View Scheme

hydrogenchloride; thallium(III) nitrate; trimethyl orthoformate 1.) methanol, 1 h, 2.) refluxed, 4 h; Yield given. Multistep reaction;