(2S)-2-[2-(4-吡啶基)乙基]哌嗪合成路线 （共 2 条）
反应条件
ammonium formate; palladium on activated charcoal in ethanol
Heating;
参考文献
ELI LILLY AND COMPANY
Patent: WO2003/82877 A1, 2003 ;
Location in patent: Page/Page column 66 ;
WO 03/082877 A1
反应条件
1: tetrahydrofuran / 24 h / 20 °C
2: Ph3P; aq. NaOH / (Ph3P)4Pd / tetrahydrofuran / Heating
3: 86 percent / ammonium formate / Pd/C / ethanol / Heating
View Scheme
参考文献
Schaus, John M.; Krushinski, Joseph H.; Ruley, Kevin M.; Rocco, Vincent P.
Synthesis, 2007 , # 15 p. 2307 - 2312
