potassium phosphate; tetrakis(triphenylphosphine) palladium(0) in N,N-dimethyl-formamide T=85°C; Suzuki cross-coupling reaction; 12 h;

1.1: B(OC4H9)3; n-BuLi / tetrahydrofuran; hexane / -78 - 20 °C 1.2: aq. HCl / tetrahydrofuran; hexane / cooling 1.3: 76 percent / MgSO4 / diethyl ether 2.1: 64.5 percent / Pd(PPh3)4; K3PO4 / dimethylformamide / 12 h / 85 °C View Scheme