3-氧代-1,3-二氢异苯并呋喃-1-膦酸二甲酯合成路线 （共 26 条）
反应条件
lithium tert-butylate
1.) THF, hexane, -78 deg C, 0.5 h, 2.) THF, hexane, a) -78 deg C, 0.5 h, b) reflux, 1 h; Yield given. Multistep reaction;
参考文献
Watanabe; Morimoto; Nogami; Ijichi; Furukawa
Chemical and Pharmaceutical Bulletin, 1993 , vol. 41, # 5 p. 968 - 970
反应条件
lithium tert-butylate
1.) THF, hexane, -78 deg C, 0.5 h, 2.) THF, hexane, a) -78 deg C, 0.5 h, b) reflux, 1 h; Yield given. Multistep reaction;
参考文献
Watanabe; Morimoto; Nogami; Ijichi; Furukawa
Chemical and Pharmaceutical Bulletin, 1993 , vol. 41, # 5 p. 968 - 970
反应条件
1: 1.) NaH / 1.) THF, 0 deg C, 45 min; 2.) 0 deg C, 5 min
2: Zn powder / acetic acid / 18 h / 90 °C
View Scheme
参考文献
Napolitano, Elio; Ramacciotti, Antonella
Gazzetta Chimica Italiana, 1987 , vol. 117, # 7 p. 443 - 444
反应条件
lithium tert-butylate
1.) THF, hexane, -78 deg C, 0.5 h, 2.) THF, hexane, a) -78 deg C, 0.5 h, b) reflux, 1 h; Yield given. Multistep reaction;
参考文献
Watanabe; Morimoto; Nogami; Ijichi; Furukawa
Chemical and Pharmaceutical Bulletin, 1993 , vol. 41, # 5 p. 968 - 970
反应条件
lithium hexamethyldisilazane
1.) THF, hexane, -78 deg C, 1 h, 2.) THF, hexane, -78 deg C, 1 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Watanabe, Mitsuaki; Ijichi, Saori; Morimoto, Hitoshi; Nogami, Kayoko; Furukawa, Sunao
Heterocycles, 1993 , vol. 36, # 3 p. 553 - 563
反应条件
lithium hexamethyldisilazane
1.) THF, hexane, -78 deg C, 1 h, 2.) THF, hexane, -78 deg C, 1 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Watanabe, Mitsuaki; Ijichi, Saori; Morimoto, Hitoshi; Nogami, Kayoko; Furukawa, Sunao
Heterocycles, 1993 , vol. 36, # 3 p. 553 - 563
