(5S)-5,6-异丙撑二氧-6-甲基-庚烷-2-酮合成路线 （共 10 条）
反应条件
potassium permanganate; tetrabutylammomium bromide in water; benzene
15 h; Ambient temperature;
参考文献
Fourneron, J. D.; Archelas, A.; Furstoss, R.
Journal of Organic Chemistry, 1989 , vol. 54, # 19 p. 4686 - 4689
反应条件
potassium permanganate; tetrabutylammomium bromide in dichloromethane
参考文献
Archelas; Delbecque; Furstoss
Tetrahedron Asymmetry, 1993 , vol. 4, # 12 p. 2445 - 2446
反应条件
1: 49 percent / H2O; ethanol / 48 h / Aspergillus niger, pH 4.8
2: 90 percent / p-toluenesulfonic acid
3: 80 percent / KMnO4, NBu4Br / H2O; benzene / 15 h / Ambient temperature
View Scheme
参考文献
Fourneron, J. D.; Archelas, A.; Furstoss, R.
Journal of Organic Chemistry, 1989 , vol. 54, # 19 p. 4686 - 4689
反应条件
1: 90 percent / p-toluenesulfonic acid
2: 80 percent / KMnO4, NBu4Br / H2O; benzene / 15 h / Ambient temperature
View Scheme
参考文献
Fourneron, J. D.; Archelas, A.; Furstoss, R.
Journal of Organic Chemistry, 1989 , vol. 54, # 19 p. 4686 - 4689
反应条件
1: NaH / diethyl ether
2: mCPA / CH2Cl2 / 5 °C
4: acid hydrolysis
5: TsOH / 90 h
6: 40 percent / KMnO4, (Bu)4NBr / CH2Cl2
View Scheme
参考文献
Archelas; Delbecque; Furstoss
Tetrahedron Asymmetry, 1993 , vol. 4, # 12 p. 2445 - 2446
反应条件
1: mCPA / CH2Cl2 / 5 °C
3: acid hydrolysis
4: TsOH / 90 h
5: 40 percent / KMnO4, (Bu)4NBr / CH2Cl2
View Scheme
参考文献
Archelas; Delbecque; Furstoss
Tetrahedron Asymmetry, 1993 , vol. 4, # 12 p. 2445 - 2446
反应条件
2: acid hydrolysis
3: TsOH / 90 h
4: 40 percent / KMnO4, (Bu)4NBr / CH2Cl2
View Scheme
参考文献
Archelas; Delbecque; Furstoss
Tetrahedron Asymmetry, 1993 , vol. 4, # 12 p. 2445 - 2446
反应条件
1: TsOH / 90 h
2: 40 percent / KMnO4, (Bu)4NBr / CH2Cl2
View Scheme
参考文献
Archelas; Delbecque; Furstoss
Tetrahedron Asymmetry, 1993 , vol. 4, # 12 p. 2445 - 2446
反应条件
1: acid hydrolysis
2: TsOH / 90 h
3: 40 percent / KMnO4, (Bu)4NBr / CH2Cl2
View Scheme
参考文献
Archelas; Delbecque; Furstoss
Tetrahedron Asymmetry, 1993 , vol. 4, # 12 p. 2445 - 2446
反应条件
1: 1.) NaH / 1.) mineral oil, hexan, THF, room temperature, 2 h, 2.) mineral oil, hexan, THF, room temperature, 16 h
2: 91 percent / DIBAH / hexane / 1 h / -10 °C
View Scheme
参考文献
Schwabe; Farkas; Pfander
Helvetica Chimica Acta, 1988 , vol. 71, # 1 p. 292 - 297
