(6S,2E)-6,7-异丙撑二氧-3,7-二甲基-2-辛烯-1-醇合成路线 （共 26 条）
反应条件
potassium carbonate in methanol
T=20°C; 0.5 h;
参考文献
Morimoto, Yoshiki; Iwai, Toshiyuki; Kinoshita, Takamasa
Tetrahedron Letters, 2001 , vol. 42, # 36 p. 6307 - 6309
反应条件
diisobutylaluminium hydride in diethyl ether; hexane
2 h; Ambient temperature;
参考文献
Meier, Heidi; Uebelhart, Peter; Eugster, Conrad Hans
Helvetica Chimica Acta, 1986 , vol. 69, p. 106 - 123
反应条件
toluene-4-sulfonic acid in acetone
T=0°C; 6 h;
参考文献
Tagami, Koichi; Liu, Chengwei; Minami, Atsushi; Noike, Motoyoshi; Isaka, Tetsuya; Fueki, Shuhei; Shichijo, Yoshihiro; Toshima, Hiroaki; Gomi, Katsuya; Dairi, Tohru; Oikawa, Hideaki
Journal of the American Chemical Society, 2013 , vol. 135, # 4 p. 1260 - 1263
反应条件
sodium hydroxide in ethanol
Heating;
参考文献
Fourneron, J. D.; Archelas, A.; Furstoss, R.
Journal of Organic Chemistry, 1989 , vol. 54, # 19 p. 4686 - 4689
反应条件
1: SeO2 / ethanol / 3 h / Heating
2: 2 percent / NaBH4 / diethyl ether; ethanol / 30 h / 0 °C
3: 79 percent / D-(-)-diisopropyl tartrate (D-(-)-DIPT), Ti(Oi-Pr)4, tert.-butyl hydroperoxide (TBHP) / CH2Cl2 / 4 h / -20 °C
5: 85 percent / 18 M H2SO4 / tetrahydrofuran; H2O / 30 h / 0 °C
6: 96 percent / p-toluenesulfonic acid / 2 h / Ambient temperature
7: 93 percent / K2CO3 / methanol / 1 h / Ambient temperature
View Scheme
参考文献
Hashimoto, Masaru; Kan, Toshiyuki; Nozaki, Koji; Yanagiya, Mitsutoshi; Shirahama, Harushia; Matsumoto, Takeshi
Journal of Organic Chemistry, 1990 , vol. 55, # 17 p. 5088 - 5107
反应条件
1: 87 percent / CSA / CH2Cl2 / 1 h / 0 °C
2: 97 percent / K2CO3 / methanol / 0.5 h / 20 °C
View Scheme
参考文献
Morimoto, Yoshiki; Iwai, Toshiyuki; Kinoshita, Takamasa
Tetrahedron Letters, 2001 , vol. 42, # 36 p. 6307 - 6309
反应条件
1: 49 percent / H2O; ethanol / 48 h / Aspergillus niger, pH 4.8
2: 90 percent / p-toluenesulfonic acid
3: 80 percent / 5 N NaOH / ethanol / Heating
View Scheme
参考文献
Fourneron, J. D.; Archelas, A.; Furstoss, R.
Journal of Organic Chemistry, 1989 , vol. 54, # 19 p. 4686 - 4689
反应条件
1: 90 percent / p-toluenesulfonic acid
2: 80 percent / 5 N NaOH / ethanol / Heating
View Scheme
参考文献
Fourneron, J. D.; Archelas, A.; Furstoss, R.
Journal of Organic Chemistry, 1989 , vol. 54, # 19 p. 4686 - 4689
反应条件
1: 79 percent / D-(-)-diisopropyl tartrate (D-(-)-DIPT), Ti(Oi-Pr)4, tert.-butyl hydroperoxide (TBHP) / CH2Cl2 / 4 h / -20 °C
3: 85 percent / 18 M H2SO4 / tetrahydrofuran; H2O / 30 h / 0 °C
4: 96 percent / p-toluenesulfonic acid / 2 h / Ambient temperature
5: 93 percent / K2CO3 / methanol / 1 h / Ambient temperature
View Scheme
参考文献
Hashimoto, Masaru; Kan, Toshiyuki; Nozaki, Koji; Yanagiya, Mitsutoshi; Shirahama, Harushia; Matsumoto, Takeshi
Journal of Organic Chemistry, 1990 , vol. 55, # 17 p. 5088 - 5107
反应条件
1: 2 percent / NaBH4 / diethyl ether; ethanol / 30 h / 0 °C
2: 79 percent / D-(-)-diisopropyl tartrate (D-(-)-DIPT), Ti(Oi-Pr)4, tert.-butyl hydroperoxide (TBHP) / CH2Cl2 / 4 h / -20 °C
4: 85 percent / 18 M H2SO4 / tetrahydrofuran; H2O / 30 h / 0 °C
5: 96 percent / p-toluenesulfonic acid / 2 h / Ambient temperature
6: 93 percent / K2CO3 / methanol / 1 h / Ambient temperature
View Scheme
参考文献
Hashimoto, Masaru; Kan, Toshiyuki; Nozaki, Koji; Yanagiya, Mitsutoshi; Shirahama, Harushia; Matsumoto, Takeshi
Journal of Organic Chemistry, 1990 , vol. 55, # 17 p. 5088 - 5107
