(S)-(-)-1-苯基-1-丙醇合成路线 （共 162 条）
反应条件
1: With titanium(IV) isopropylate; (Sa)-2'-[(R)-hydroxy(phenyl)methyl]-(1,1'-binaphthalen)-2-ol in diethyl ether; hexane T=0°C; 3 h; Inert atmosphere; 2: With hydrogenchloride in diethyl ether; water; toluene Inert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Tetrahedron Asymmetry, , vol. 23, # 10 p. 789 - 794
反应条件
di-μ-chloro-bis(η4-1,5-cyclooctadiene)diiridium; (R)-N-(3-methylpyridyl-2-methyl)-7-di-(3,5-di-tert-butylphenyl)phosphino-7'-amino-1,1'-spiro-dihydro-indene; potassium tert-butylate; hydrogen in ethanol T=25 - 30°C; P=7600.51 Torr; 0.666667 h; Autoclave; optical yield given as percent eeenantioselective reaction;
参考文献
Angewandte Chemie - International Edition, , vol. 50, # 32 p. 7329 - 7332
反应条件
Arthrobacter atrocyaneus in N,N-dimethyl-formamide T=32°C; 48 h; Microbiological reaction; enantioselective reaction;
参考文献
Journal of Molecular Catalysis B: Enzymatic, , vol. 83, p. 23 - 28
反应条件
(1S,2R)-(+)-N,N-dimethylephedrinium bis(trifluoromethanesulfon)imidate in dichloromethane T=120°C;
参考文献
Analytical Chemistry, , vol. 76, # 22 p. 6819 - 6822
反应条件
(1S,2R)-(-)-2-(N,N-di-n-butylamino)-1-phenylpropan-1-ol in hexane 1.) r.t., 20 min; 2.) 0 deg C, 16 h;
参考文献
Journal of the Chemical Society, Chemical Communications, , # 22 p. 1690 - 1691
反应条件
dimethylsulfide borane complex; (S)-2-(anilinodiphenylmethyl)pyrrolidine in tetrahydrofuran T=20°C; 2 h; enantioselective reaction;
参考文献
Tetrahedron, , vol. 69, # 6 p. 1739 - 1746
反应条件
Candida antarctica lipase B; (η5-C5Ph5)Ru(CO)2Cl; potassium tert-butylate; sodium carbonate in tetrahydrofuran; toluene T=20°C; 17 h;
参考文献
Journal of the American Chemical Society, , vol. 127, # 24 p. 8817 - 8825
反应条件
titanium(IV) isopropylate; methyl 4,6-O-PhCH-2-deoxy-2-p-TsNH-α-D-glucopyranoside in dichloromethane; toluene T=20°C; 3 h; Product distribution; Further Variations:CatalystsTemperaturesamounts of catalyst; reaction times;
参考文献
Tetrahedron Asymmetry, , vol. 13, # 1 p. 77 - 82
反应条件
sodium hydroxide; (-)-isopinocampheylborane; dihydrogen peroxide 1) THF, -25 deg C, 9 h, 2) 50 deg C, 1 h; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 46, # 24 p. 5047 - 5048
反应条件
Arthrobacter atrocyaneus in N,N-dimethyl-formamide T=32°C; 72 h; Microbiological reaction; enantioselective reaction;
参考文献
Journal of Molecular Catalysis B: Enzymatic, , vol. 83, p. 23 - 28
