(S)-(-)-1-苯基-1-丙醇合成路线 （共 162 条）
反应条件
potassium fluoride; dihydrogen peroxide; potassium hydrogencarbonate in tetrahydrofuran; methanol 16 h; Inert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Organic and Biomolecular Chemistry, , vol. 7, # 21 p. 4470 - 4474
反应条件
[Ru2(p-PriC6H4Me)2(μ-Cl)Cl]2; 4-hydroxybutanol; N-[(1S,2S)-2-amino-1,2-diphenylethyl]-p-tolylsulphonamide; potassium hydroxide T=110°C; 72 h; optical yield given as percent ee;
参考文献
Chemistry - An Asian Journal, , vol. 5, # 3 p. 538 - 542
反应条件
Pseudomonas fluorescence lipase Resolution of racemateEnzymatic reaction; optical yield given as percent ee;
参考文献
European Journal of Organic Chemistry, , # 24 p. 4588 - 4616
反应条件
1: With CF3O3S(1-)*C45H39N2OPRh(1+); benzo[1,3,2]dioxaborole in tetrahydrofuran T=20°C; Inert atmosphere; 2: With dihydrogen peroxide; sodium hydroxide in ethanol; water T=0 - 20°C; optical yield given as percent eeenantioselective reaction;
参考文献
Tetrahedron Asymmetry, , vol. 21, # 11-12 p. 1458 - 1473
反应条件
Novozym 435 in 2,2,4-trimethylpentane T=47°C; 3 h; Molecular sieveEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Preparative Biochemistry and Biotechnology, , vol. 40, # 4 p. 389 - 404
反应条件
C32H31Cl2N4OPRu; potassium isopropoxide T=40°C; P=750.075 Torr; 0.666667 h; Inert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Chemistry - A European Journal, , vol. 18, # 35 p. 10843 - 10846
反应条件
2-acetyloxy-1-propene; lipase YS in di-isopropyl ether T=30°C; 200 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 10 p. 1253 - 1256
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran 12 h; Inert atmosphere; optical yield given as percent ee;
参考文献
Organic and Biomolecular Chemistry, , vol. 6, # 10 p. 1831 - 1842
反应条件
1: With CF3O3S(1-)*C45H39N2OPRh(1+); benzo[1,3,2]dioxaborole in tetrahydrofuran T=0°C; Inert atmosphere; 2: With dihydrogen peroxide; sodium hydroxide in ethanol; water T=0 - 20°C; optical yield given as percent eeenantioselective reaction;
参考文献
Tetrahedron Asymmetry, , vol. 21, # 11-12 p. 1458 - 1473
反应条件
1: alpha-Phenylpropyl alcohol With (S,R(P))-2-phenyl-2,3-dihydroimidazo[1,2-a]pyrindinyl-pentaphenylcyclopentadienyliron; N-ethyl-N,N-diisopropylamine in toluene T=0°C; 0.0833333 h; 2: 2-methylpropanoic anhydride in toluene T=0°C; 7 h; optical yield given as percent eeenantioselective reaction;
参考文献
Journal of the American Chemical Society, , vol. 132, # 47 p. 17041 - 17044
