(S)-(-)-1-苯基-1-丙醇合成路线 (共 162 条)
反应条件
1: alpha-Phenylpropyl alcohol With (S,R(P))-2-phenyl-2,3-dihydroimidazo[1,2-a]pyrindinyl-pentaphenylcyclopentadienyliron; N-ethyl-N,N-diisopropylamine in toluene T=0°C; 0.0833333 h; 2: propionic acid anhydride in toluene T=0°C; 7 h; optical yield given as percent eeenantioselective reaction;
参考文献
Journal of the American Chemical Society, , vol. 132, # 47 p. 17041 - 17044
反应条件
Novozym 435 in 2,2,4-trimethylpentane T=40°C; 0.5 h; Molecular sieveEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Preparative Biochemistry and Biotechnology, , vol. 40, # 4 p. 389 - 404
反应条件
lipase YS in di-isopropyl ether T=30°C; 200 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 10 p. 1253 - 1256
反应条件
in acetonitrile T=27 - 28°C; 0.1 M aq. phosphate buffer (pH 8.0), penicillin G aminohydrolase (PGA); Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Tetrahedron Asymmetry, , vol. 4, # 5 p. 1031 - 1034
反应条件
Birman's catalyst; trimethylacetic anhydride; N-ethyl-N,N-diisopropylamine in dichloromethane T=20°C; 12 h; optical yield given as percent eeenantioselective reaction;
参考文献
Heterocycles, , vol. 77, # 2 p. 801 - 810
反应条件
1: diethylzinc; phenylacetylene With chiral bicyclo[3.2.1]octane-based alcohol in tetrahydrofuran; hexane 1 h; 2: benzaldehyde in tetrahydrofuran; hexane T=0°C; 24 h; Further byproducts given. Title compound not separated from byproducts;
参考文献
Tetrahedron Asymmetry, , vol. 17, # 9 p. 1409 - 1414
反应条件
2: K2CO3 / methanol / Ambient temperature View Scheme
参考文献
Journal of the Chemical Society, Chemical Communications, , p. 598 - 600
反应条件
2: K2CO3 / methanol / Ambient temperature View Scheme
参考文献
Journal of the Chemical Society, Chemical Communications, , p. 598 - 600
反应条件
water; sodium hydroxide T=20°C; 2 h;
参考文献
Letters in Organic Chemistry, , vol. 9, # 9 p. 615 - 621
反应条件
water; sodium hydroxide T=20°C; 2 h;
参考文献
Letters in Organic Chemistry, , vol. 9, # 9 p. 615 - 621