(S)-(-)-1-苯基-1-丙醇合成路线 （共 162 条）
反应条件
benzoic acid anhydride; N-ethyl-N,N-diisopropylamine in dichloromethane T=20°C; 12 h; Title compound not separated from byproducts.;
参考文献
Tetrahedron Letters, , vol. 48, # 47 p. 8314 - 8317
反应条件
lipase B from Candida antarctica in cyclohexane T=50°C; 0.75 h; Resolution of racemate; optical yield given as percent ee;
参考文献
Journal of Catalysis, , vol. 288, p. 24 - 32
反应条件
yeast strain Aureobasidium pullulans CQA T=28°C; 48 h; Microbiological reactionEnzymatic reaction;
参考文献
Journal of Molecular Catalysis B: Enzymatic, , vol. 102, p. 94 - 98
反应条件
1: isopropyl alcohol With [Ru(1,5-cyclooctadiene)Cl2]x; (8R,9R)-9-amino-(9-deoxy)epiquinine T=20°C; 0.5 h; Inert atmosphere; 2: With potassium hydroxide 0.5 h; Inert atmosphere; 3: 1-phenyl-propan-1-one T=0°C; 96 h; Inert atmosphere; enantioselective reaction;
参考文献
Journal of Chemical Research, , vol. 37, # 12 p. 761 - 763
反应条件
nicotinamide; sodium phosphate buffer; G6P; NADP; magnesium chloride in water T=37°C; 1 h; biotransformation with phenobarbital-pretreated rat-liver (S-9);
参考文献
Heterocycles, , vol. 42, # 2 p. 831 - 836
反应条件
(-)-erythro-PMPM in hexane T=0°C;
参考文献
Journal of the Chemical Society, Chemical Communications, , # 6 p. 467 - 468
反应条件
potassium fluoride; dihydrogen peroxide; potassium hydrogencarbonate in tetrahydrofuran; methanol T=20°C; 11 h;
参考文献
Journal of Organic Chemistry, , vol. 66, # 4 p. 1441 - 1449
反应条件
novozyme 435 in toluene T=60°C; 4 h;
参考文献
Tetrahedron Asymmetry, , vol. 18, # 13 p. 1618 - 1624
反应条件
1: 279.8 mg / NaI / 1,2-dimethoxy-ethane / 12 h / Heating 2: 100 percent / sym-collidine / CH2Cl2 / 0.25 h / -78 °C 3: 99 percent / H2 / Rh-Al2O3 / tetrahydrofuran / 12 h / 760.05 Torr 4: 60 percent / Na(Hg) / methanol; H2O / 0.75 h 5: 75 percent / Et3N / CH2Cl2 / 0.17 h / -78 °C 6: 100 percent / H2; Et3N / Pd/C / ethyl acetate / 3 h / 760.05 Torr 7: Bu4NF / tetrahydrofuran / 12 h View Scheme
参考文献
Chemical Communications, , # 21 p. 2151 - 2153
反应条件
1: 100 percent / sym-collidine / CH2Cl2 / 0.25 h / -78 °C 2: 99 percent / H2 / Rh-Al2O3 / tetrahydrofuran / 12 h / 760.05 Torr 3: 60 percent / Na(Hg) / methanol; H2O / 0.75 h 4: 75 percent / Et3N / CH2Cl2 / 0.17 h / -78 °C 5: 100 percent / H2; Et3N / Pd/C / ethyl acetate / 3 h / 760.05 Torr 6: Bu4NF / tetrahydrofuran / 12 h View Scheme
参考文献
Chemical Communications, , # 21 p. 2151 - 2153
