(S)-(-)-1-苯基-1-丙醇合成路线 （共 162 条）
反应条件
Birman's catalyst; nicotinic anhydride in dichloromethane T=0°C; 12 h; Resolution of racemate; optical yield given as percent eeenantioselective reaction;
参考文献
Heterocycles, , vol. 80, # 1 p. 169 - 175
反应条件
Birman's catalyst; nicotinic anhydride in dichloromethane T=0°C; 12 h; Inert atmosphereResolution of racemate; Reagent/catalyst; enantioselective reaction;
参考文献
Helvetica Chimica Acta, , vol. 95, # 10 p. 1891 - 1911,21
Helvetica Chimica Acta, , vol. 95, # 10 p. 1891 - 1911
反应条件
formic acid; [(R,R)-N-(p-toluenesulfonyl)-1,2-diphenylethylenediamine](p-cymene)ruthenium; triethylamine in ethyl acetate T=20°C; 168 h; Inert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Acta Poloniae Pharmaceutica - Drug Research, , vol. 67, # 6 p. 717 - 721
反应条件
(R)-(+)-N-methylbenzoguanidine; trimethylacetic anhydride in diethyl ether T=20°C; 12 h; Resolution of racemate; optical yield given as percent ee;
参考文献
Organic and Biomolecular Chemistry, , vol. 9, # 20 p. 7092 - 7096
反应条件
1: 1-phenyl-propan-1-one With aluminum oxide; sodium tetrahydroborate in hexane T=40°C; 3 h; 2: 2-acetyloxy-1-propene With Lipase 'Amano' PS-C II in hexane T=25°C; 4 h;
参考文献
Tetrahedron Asymmetry, , vol. 13, # 8 p. 815 - 820
反应条件
(R)-(+)-N-methylbenzoguanidine; trimethylacetic anhydride in diethyl ether T=20°C; 12 h; Resolution of racemate; optical yield given as percent ee;
参考文献
Organic and Biomolecular Chemistry, , vol. 9, # 20 p. 7092 - 7096
反应条件
trimethylacetic anhydride; (-)-Tetramisole in diethyl ether T=20°C; 12 h; Resolution of racemate; optical yield given as percent ee;
参考文献
Organic and Biomolecular Chemistry, , vol. 9, # 20 p. 7092 - 7096
反应条件
(R)-C56H70O6 in toluene T=0°C; 20 h; Yield givenYields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 64, # 12 p. 4222 - 4223
反应条件
1: With 4-(N,N-dimethlyamino)pyridine; dicyclohexyl-carbodiimide in dichloromethane T=20°C; Inert atmosphere; 2: With immobilized Candida antarctica Lipase B; water in hexane T=30°C; pH=6.5; 24 h; aq. phosphate bufferEnzymatic reaction; 3: With water; sodium hydroxide in methanol T=20°C; 1 h; optical yield given as percent eeenantioselective reaction;
参考文献
Tetrahedron, , vol. 66, # 40 p. 8060 - 8067
反应条件
Toyonite-200M-supported Burkholderia cepacia lipase I287F/I290A mutant in di-isopropyl ether T=30°C; 50 h; Molecular sieveEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Organic and Biomolecular Chemistry, , vol. 10, # 31 p. 6299 - 6308
