1: LiAlH4, LiI / various solvent(s); toluene / 0.5 h / -20 - -13 °C 2: 50 percent / Et3N, pancreatin, vinyl acetate / various solvent(s) / 7 h / Ambient temperature 3: DMAP / pyridine / 16 h / Ambient temperature 4: p-TsOH / ethanol / 2 h / Ambient temperature View Scheme

1: LiAlH4, LiI / various solvent(s); toluene / 0.5 h / -20 - -13 °C 2: 45 percent / Et3N, pancreatin, vinyl acetate / various solvent(s) / 7 h / Ambient temperature 3: p-TsOH / ethanol / 2 h / Ambient temperature View Scheme

acetic acid 15 h; Ambient temperature;