(R)-1-苯基-2-丙炔-1-醇合成路线 （共 19 条）
反应条件
tetrabutyl ammonium fluoride; water in tetrahydrofuran T=0 - 20°C; 12 h;
参考文献
Journal of Organic Chemistry, , vol. 67, # 3 p. 640 - 647
参考文献
Ariza, Xavier; Garcia, Jordi; Georges, Yohan; Vicente, Mar
Organic Letters, 2006 , vol. 8, # 20 p. 4501 - 4504
反应条件
Pseudomonas monteilii TA-5 in methanol T=30°C; pH=7; 7 h; aq. phosphate buffer; optical yield given as percent eeenantioselective reaction;
参考文献
Chen, Yongzheng; Lie, Felicia; Li, Zhi
Advanced Synthesis and Catalysis, 2009 , vol. 351, # 13 p. 2107 - 2112
反应条件
ueber das Cinchonin-Salz des 2-Carboxy-3-nitro-benzoyl-Derivats;
参考文献
Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, , vol. 298, p. 87,91
Yakugaku Zasshi, , vol. 80, p. 156
Chem.Abstr., , vol. 54, # 13061
反应条件
ChiroCLEC-PC; water in toluene Acetylation; enzymatic resolution; 6.5 h; Enzymatic reaction; Product distribution; Further Variations:reaction time;
参考文献
Journal of Organic Chemistry, , vol. 65, # 6 p. 1788 - 1792
反应条件
toluene-4-sulfonic acid in dichloromethane 2 h;
参考文献
Noe, Christian R.; Knollmueller, Max; Oberhauser, Berndt; Steinbauer, Gerhard; Wagner, Ernst
Chemische Berichte, 1986 , vol. 119, # 2 p. 729 - 743
反应条件
N,N,N',N',N'',N''-hexamethylphosphoric triamide; n-butyllithium in tetrahydrofuran T=-42 - 20°C;
参考文献
Tetrahedron Letters, , vol. 43, # 45 p. 8043 - 8045
反应条件
1: acetyl chloride With 1,4-diaza-bicyclo[2.2.2]octane; (S)-3,3'-bis-(2,4,6-triisopropylphenyl)-BINOL phosphoric acid in diethyl ether T=20°C; 0.0833333 h; Inert atmosphereResolution of racemate; 2: 3-hydroxy-3-phenyl-prop-1-yne in diethyl ether T=-20°C; 5 h; Resolution of racemateInert atmosphere; optical yield given as percent ee;
参考文献
Organic Letters, , vol. 14, # 13 p. 3486 - 3489
反应条件
phosphate buffer 4.8 h; Ambient temperatureSAM II lipase;
参考文献
Waldinger, Claudia; Schneider, Manfred; Botta, Maurizio; Corelli, Federico; Summa, Vincenzo
Tetrahedron Asymmetry, 1996 , vol. 7, # 5 p. 1485 - 1488
反应条件
1: p-TsOH / CH2Cl2 / 20 °C 2: DIBAL-H / tetrahydrofuran / 0 - 20 °C 3: NCS; Ph3P / CH2Cl2 / 0 - 20 °C 4: n-BuLi; HMPA / tetrahydrofuran / -42 - 20 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 43, # 45 p. 8043 - 8045
