1: formaldehyd; morpholine*TFA in 1-methyl-pyrrolidin-2-one T=20 - 40°C; 2: 4-bromobenzylzinc bromide in tetrahydrofuran; 1-methyl-pyrrolidin-2-one T=20 - 34°C; Mannich reaction; 0.166667 h;

in diethyl ether T=0°C;