2-(4-甲基-2-苯基-1-哌嗪基)-3-吡啶甲醇合成路线 （共 6 条）
反应条件
in tetrahydrofuran; water
参考文献
Sumika Fine Chemicals Co., Ltd.
Patent: US2002/35255 A1, 2002 ;
反应条件
sulfuric acid; water; hydrogen; 5percent palladium-carbon catalyst deactivated with iron sulfate T=25 - 70°C; P=2205.22 Torr; 5 - 20 h; Product distribution / selectivity;
参考文献
Sumitomo Chemical Company, Limited
Patent: EP1953150 A1, 2008 ;
Location in patent: Page/Page column 3-4 ;
反应条件
1: 99 percent / potassium fluoride / dimethylformamide / 6 h / 140 °C 2: 63 percent / sodium hydroxide / ethane-1,2-diol / 7 h / 130 °C 3: 97 percent / sodium bis(2-methoxyethoxy)aluminum hydride / toluene / 2 h / 55 - 60 °C View Scheme
参考文献
Organic Preparations and Procedures International, , vol. 39, # 4 p. 399 - 402
反应条件
1: 99 percent / potassium fluoride / dimethylformamide / 6 h / 140 °C 2: 63 percent / sodium hydroxide / ethane-1,2-diol / 7 h / 130 °C 3: 97 percent / sodium bis(2-methoxyethoxy)aluminum hydride / toluene / 2 h / 55 - 60 °C View Scheme
参考文献
Organic Preparations and Procedures International, , vol. 39, # 4 p. 399 - 402
反应条件
1: With sulfuric acid T=30 - 40°C; Inert atmosphere; 2: With sodium hydroxide in water; isopropyl alcohol T=13 - 33°C; pH=1.5 - 11.2; Product distribution / selectivity;
参考文献
Sumitomo Chemical Company, Limited
Patent: EP2135870 A1, 2009 ;
Location in patent: Page/Page column 5-6 ;
参考文献
Singer, Claude; Liberman, Anita; Finkelstein, Nina
Patent: US2001/51718 A1, 2001 ;
Title/Abstract Full Text Show Details
Singer, Claude; Liberman, Anita; Finkelstein, Nina
Patent: US2003/69417 A1, 2003 ;
