6-溴-1,2,3,4-四氢-萘合成路线 （共 12 条）
反应条件
acetic acid; Zinc chloride in (2S)-N-methyl-1-phenylpropan-2-amine hydrate; water
参考文献
Takiguchi, Takao; Tsuboyama, Akira; Mizutani, Hidemasa; Okada, Shinjiro; Miura, Seishi; Moriyama, Takashi; Igawa, Satoshi; Kamatani, Jun; Furugori, Manabu
Patent: US2002/64681 A1, 2002 ;
反应条件
triethylsilane; trifluoroacetic acid T=20 - 50°C; 4 h;
参考文献
Nissan Chemical Industries, Ltd.
Patent: US2012/209005 A1, 2012 ;
Location in patent: Page/Page column 30 ;
反应条件
benzyltrimethylammonium bromide dibromide; zinc(II) chloride in acetic acid 1 h; Ambient temperature;
参考文献
Kajigaeshi, Shoji; Kakinami, Takaaki; Moriwaki, Masayuki; Tanaka, Toshio; Fujisaki, Shizuo; Okamoto, Tsuyoshi
Bulletin of the Chemical Society of Japan, 1989 , vol. 62, # 2 p. 439 - 443
反应条件
bromine; iron in tetrachloromethane 20 h; Ambient temperature; Product distribution;
参考文献
Bulletin de la Societe Chimique de France, , vol. 2, # 3-4 p. 96 - 104
反应条件
sulfuric acid Diazotization.Behandlung der Diazoniumsalz-Loesung mit CuBr in wss. HBr;
参考文献
Journal of the Chemical Society, , p. 1532,1536
反应条件
1: polyphosphoric acid / 1 h / 90 °C 2: trifluoroacetic acid; triethylsilane / 4 h / 20 - 50 °C View Scheme
反应条件
1: With n-butyllithium in Dry THF; hexane T=-78 - 25°C; 1.16667 h; 2: With hydrogenchloride pH=1;
参考文献
ASTRAZENECA AB
Patent: WO2004/792 A1, 2003 ;
Location in patent: Page 22 ;
反应条件
dann in saurer Loesung;
参考文献
v. Braun
Chemische Berichte, 1923 , vol. 56, p. 2338
反应条件
1: With n-butyllithium in Dry THF; hexane T=-78 - 25°C; 1.16667 h; 2: With hydrogenchloride pH=1;
参考文献
WO2004/792 A1, ;
Page 22 ;
反应条件
1: With 1-methyl-pyrrolidin-2-one; copper (I) cyanide T=130°C; 40 h; Under dry nitrogen; 2: With 1-methyl-pyrrolidin-2-one 3 h;
参考文献
ASTRAZENECA AB
Patent: WO2004/792 A1, 2003 ;
Location in patent: Page 21 ;
