alpha-丁基-beta-氧代苯丙酸乙酯合成路线 （共 7 条）
反应条件
1: ethyl 3-oxo-3-phenylpropionate With sodium hydride in tetrahydrofuran
T=0 - 20°C;
2: 1-bromo-butane in tetrahydrofuran
T=50°C;
参考文献
Malkov, Andrei V.; Stoncius, Sigitas; Vrankova, Kvetoslava; Arndt, Matthias; Kocovsky, Pavel
Chemistry - A European Journal, 2008 , vol. 14, # 27 p. 8082 - 8085
反应条件
diethyl ether
Erwaermen des danach isolierten Reaktionsprodukts mit Toluol-sulfonsaeure-(4) in Benzol;
参考文献
Breslow; Baumgarten; Hauser
Journal of the American Chemical Society, 1944 , vol. 66, p. 1286
反应条件
1: CH2Cl2
View Scheme
参考文献
Newman,M.S.; Stalick,W.M.
Journal of Organic Chemistry, 1973 , vol. 38, p. 3386 - 3389
参考文献
Henecka
Chemische Berichte, 1948 , vol. 81, p. 197,208
Full Text Show Details
Wojack
Chemische Berichte, 1938 , vol. 71, p. 1102,1114
参考文献
Newman,M.S.; Stalick,W.M.
Journal of Organic Chemistry, 1973 , vol. 38, p. 3386 - 3389
反应条件
(i) THF, (ii) /BRN= 506893/, (iii) aq. H2O2, aq. HCl, MeOH; Multistep reaction;
参考文献
Muraki,M. et al.
Bulletin of the Chemical Society of Japan, 1975 , vol. 48, p. 3200 - 3204
参考文献
Searle and Co.
Patent: US2740785 , 1954 ;
