3-(二甲基氨基)环己-2-烯-1-酮合成路线 （共 6 条）
反应条件
potassium carbonate in dichloromethane; water
0.5 h; Ambient temperature;
参考文献
Kowalski, Conrad J.; Fields, Kevin W.
Journal of Organic Chemistry, 1981 , vol. 46, p. 197 - 201
反应条件
in benzene
8 h; Heating;
参考文献
Chen, Yuhpyng Liang; Mariano, Patrick S.; Little, Garrick M.; O'Brien, Daniel; Huesmann, Peter L.
Journal of Organic Chemistry, 1981 , vol. 46, # 23 p. 4643 - 4654
反应条件
1: 92 percent / potassium carbonate / CH2Cl2 / 2 h / Ambient temperature
2: 93 percent / potassium carbonate / CH2Cl2; H2O / 0.5 h / Ambient temperature
View Scheme
参考文献
Kowalski, Conrad J.; Fields, Kevin W.
Journal of Organic Chemistry, 1981 , vol. 46, p. 197 - 201
反应条件
lithium hexamethyldisilazane
1) THF, 0 deg C, 15 h, 2) 0 deg C, 30 min; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Chen, Yuhpyng Liang; Mariano, Patrick S.; Little, Garrick M.; O'Brien, Daniel; Huesmann, Peter L.
Journal of Organic Chemistry, 1981 , vol. 46, # 23 p. 4643 - 4654
反应条件
lithium diisopropyl amide
multistep reaction: regiochemistry of alkylation, kinetic dianion formation control; different molar ratios of base/enone, different times; other substrates; Product distribution;
参考文献
Chen, Yuhpyng Liang; Mariano, Patrick S.; Little, Garrick M.; O'Brien, Daniel; Huesmann, Peter L.
Journal of Organic Chemistry, 1981 , vol. 46, # 23 p. 4643 - 4654
反应条件
sodium acetate; zinc in acetic acid
Heating;
参考文献
Elghamry, Ibrahim
Synthetic Communications, 2002 , vol. 32, # 6 p. 897 - 902
