(2-氧代丙氧基)-乙酸甲酯合成路线 （共 7 条）
反应条件
sodium t-butanolate in tetrahydrofuran T=65°C; 1.08333 h;
参考文献
Li, Wenke; Wayne, Gregory S.; Lallaman, John E.; Chang, Sou-Jen; Wittenberger, Steven J.
Journal of Organic Chemistry, 2006 , vol. 71, # 4 p. 1725 - 1727
反应条件
hydrogenchloride; sulfuric acid in methanol
参考文献
Altenbach, Robert J.; Rotert, Gary A.; Carroll, William A.; Gopalakrishnan, Murali; Molinari, Eduardo Jose Vicente; Davis-Taber, Rachel A.; Scott, Victoria Eleanor Sarah
Patent: US2003/65182 A1, 2003 ;
US 20030065182 A1
反应条件
sulfuric acid; mercury(II) diacetate in methanol; water
0.333333 h; Heating;
参考文献
Altenbach, Robert J.; Agrios, Konstantinos; Drizin, Irene; Carroll, William A.
Synthetic Communications, 2004 , vol. 34, # 4 p. 557 - 565
反应条件
potassium osmate(VI); sodium periodate in tetrahydrofuran; water
T=20°C; 11 h;
参考文献
Li, Wenke; Wayne, Gregory S.; Lallaman, John E.; Chang, Sou-Jen; Wittenberger, Steven J.
Journal of Organic Chemistry, 2006 , vol. 71, # 4 p. 1725 - 1727
反应条件
sulfuric acid; mercury(II) diacetate
1 h; Reflux;
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH; VAN DER VEEN, Lars; MC CONNELL, Darryl; SCHNEIDER, Siegfried; GRAUERT, Matthias; SCHOOP, Andreas; WUNBERG, Tobias
Patent: WO2010/122091 A1, 2010 ;
Location in patent: Page/Page column 37 ;
WO 2010/122091 A1
反应条件
1: 79 percent Chromat. / Amberlyst-15 ion-exchange resin / 8 h / 60 °C
2: 89 percent Chromat. / potassium osmate dihydrate; sodium periodate / H2O; tetrahydrofuran / 11 h / 20 °C
View Scheme
参考文献
Li, Wenke; Wayne, Gregory S.; Lallaman, John E.; Chang, Sou-Jen; Wittenberger, Steven J.
Journal of Organic Chemistry, 2006 , vol. 71, # 4 p. 1725 - 1727
反应条件
(i) CdCl2, Et2O, (ii) /BRN= 1766346/, benzene; Multistep reaction;
参考文献
Terasawa,T.; Okada,T.
Journal of Organic Chemistry, 1977 , vol. 42, # 7 p. 1163 - 1169
