反-4-氨基环己甲酸甲酯盐酸盐合成路线 (共 2 条)
反应条件
thionyl chloride T=-10°C; 1.5 h; Reflux;
参考文献
ARRAY BIOPHARMA INC.; ALLEN, Shelley; ANDREWS, Steven S.; CONDROSKI, Kevin Ronald; HAAS, Julia; HUANG, Lily; JIANG, Yutong; KERCHER, Timothy; SEO, Jeongbeob
Patent: WO2011/6074 A1, 2011 ;
Location in patent: Page/Page column 95 ;
反应条件
hydrogenchloride in 1,4-dioxane T=20°C; 19 h;
参考文献
EP1582521 A1, ;
Page/Page column 117 ;