4-溴-3,5-二甲氧基苯甲醇合成路线 （共 6 条）
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=0 - 20°C; 8.25 h; Inert atmosphere;
参考文献
Saeed, Aamer; Mahesar, Parvez Ali
Tetrahedron, 2014 , vol. 70, # 7 p. 1401 - 1407
反应条件
dimethylsulfide borane complex in tetrahydrofuran T=40°C;
参考文献
Tan, Jason Samuel; Ciufolini, Marco A.
Organic Letters, 2006 , vol. 8, # 21 p. 4771 - 4774
反应条件
n-butyllithium; 1,2-dibromo-1,1,2,2-tetrafluoroethane; potassium tert-butylate in tetrahydrofuran; hexane -78 deg C; -78 deg C, 4.5 h; -78 deg C, 10 min;
参考文献
Australian Journal of Chemistry, , vol. 50, # 8 p. 831 - 840
反应条件
1: potassium carbonate; dimethyl sulfate / acetone / 24 h / |Reflux; |Inert atmosphere 2: lithium aluminium tetrahydride / tetrahydrofuran / 8.25 h / 0 - 20 °C / |Inert atmosphere View Scheme
参考文献
Tetrahedron, , vol. 70, # 7 p. 1401 - 1407
参考文献
WELICHEM BIOTECH, INC.
Patent: US2005/59733 A1, 2005 ;
US 20050059733 A1
参考文献
Eisai RandD Management Co., Ltd.
Patent: US2011/86882 A1, 2011 ;
Location in patent: Page/Page column 29 ;
US 20110086882 A1
