(E,Z)-十三碳-4,7-二烯-1-基乙酸酯合成路线 （共 7 条）
反应条件
pyridine in diethyl ether
4 h; Ambient temperature;
参考文献
Ishchenko, R. I.; Kovalev, B. G.
Journal of Organic Chemistry USSR (English Translation), 1989 , vol. 25, # 2.1 p. 258 - 262
Zhurnal Organicheskoi Khimii, 1989 , vol. 25, # 2 p. 291 - 296
反应条件
1: 1.) C2H5MgBr, 2.) cuprous chloride / 1.) THF, reflux, 3 h, 2.) a). 20 deg C, 2 h, b). 65 deg C, 12 h
2: 90 percent / hydrogen, nickel acetate, sodium borohydride, ethylenediamine / ethanol
3: 95 percent / pyridine / diethyl ether / 4 h / Ambient temperature
View Scheme
参考文献
Ishchenko, R. I.; Kovalev, B. G.
Journal of Organic Chemistry USSR (English Translation), 1989 , vol. 25, # 2.1 p. 258 - 262
Zhurnal Organicheskoi Khimii, 1989 , vol. 25, # 2 p. 291 - 296
反应条件
1: 90 percent / hydrogen, nickel acetate, sodium borohydride, ethylenediamine / ethanol
2: 95 percent / pyridine / diethyl ether / 4 h / Ambient temperature
View Scheme
参考文献
Ishchenko, R. I.; Kovalev, B. G.
Journal of Organic Chemistry USSR (English Translation), 1989 , vol. 25, # 2.1 p. 258 - 262
Zhurnal Organicheskoi Khimii, 1989 , vol. 25, # 2 p. 291 - 296
反应条件
1: 1.) C2H5MgBr, 2.) cuprous chloride / 1.) THF, reflux, 3 h, 2.) a). 20 deg C, 2 h, b). 65 deg C, 12 h
2: 90 percent / hydrogen, nickel acetate, sodium borohydride, ethylenediamine / ethanol
3: 95 percent / pyridine / diethyl ether / 4 h / Ambient temperature
View Scheme
参考文献
Ishchenko, R. I.; Kovalev, B. G.
Journal of Organic Chemistry USSR (English Translation), 1989 , vol. 25, # 2.1 p. 258 - 262
Zhurnal Organicheskoi Khimii, 1989 , vol. 25, # 2 p. 291 - 296
反应条件
1.1: EtMgBr / tetrahydrofuran / 2 h / 20 °C
1.2: cuprous cyanide / hexamethylphosphoric acid triamide; tetrahydrofuran / 50 °C
2.1: conc. H2SO4 / CCl4 / Heating
3.1: LiAlH4 / tetrahydrofuran
4.1: pyridine / 24 h / 20 °C
5.1: NiP-2
View Scheme
参考文献
Gansca, Lucia; Gocan, Alexandra; Oprean, Ioan; Maxim, Sanda; Budae, Iuliana
Revue Roumaine de Chimie, 2001 , vol. 46, # 11 p. 1243 - 1248
反应条件
1: LiAlH4 / tetrahydrofuran
2: pyridine / 24 h / 20 °C
3: NiP-2
View Scheme
参考文献
Gansca, Lucia; Gocan, Alexandra; Oprean, Ioan; Maxim, Sanda; Budae, Iuliana
Revue Roumaine de Chimie, 2001 , vol. 46, # 11 p. 1243 - 1248
反应条件
1: conc. H2SO4 / CCl4 / Heating
2: LiAlH4 / tetrahydrofuran
3: pyridine / 24 h / 20 °C
4: NiP-2
View Scheme
参考文献
Gansca, Lucia; Gocan, Alexandra; Oprean, Ioan; Maxim, Sanda; Budae, Iuliana
Revue Roumaine de Chimie, 2001 , vol. 46, # 11 p. 1243 - 1248
