4-硝基-1,3-二氢-2H-吲哚-2-酮合成路线 (共 3 条)
反应条件
1: With N-chloro-succinimide in chloroform
30 h; Heating / reflux;
2: With phosphoric acid; water; acetic acid
T=70°C; 1.53333 h;
3: With sodium hydroxide; sodium hydrogencarbonate
more than 3 stages;
参考文献
MERCK and CO., INC.
Patent: WO2007/61692 A2, 2007 ;
Location in patent: Page/Page column 91 ;
WO 2007/061692 A2
反应条件
iron; acetic acid in water
T=40 - 60°C; 4 h;
参考文献
SCHERING AKTIENGESELLSCHAFT
Patent: WO2005/34939 A1, 2005 ;
Location in patent: Page/Page column 74 ;
反应条件
palladium in methanol
参考文献
The Procter and Gamble Company
Patent: US6162818 A1, 2000 ;
US 6162818 A