3-(4-溴苯基)-1,2-丙烷二醇合成路线 (共 3 条)
反应条件
osmium(VIII) oxide; 4-methylmorpholine N-oxide in water; acetone
T=20°C; 2 h;
参考文献
ACTELION PHARMACEUTICALS LTD.
Patent: US2008/194670 A1, 2008 ;
Location in patent: Page/Page column 20 ;
反应条件
in chloroform; water
参考文献
Janssen Pharmaceutica N.V.
Patent: US4101666 A1, 1978 ;
反应条件
1: hydrogenchloride / tetrahydrofuran
2: NMO / OsO4 / water; acetone
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参考文献
Actelion Pharmaceuticals Ltd.
Patent: EP1863475 B1, 2011 ;