hydrogenchloride T=110 - 120°C; im Rohr;

potassium cyanide in N,N-dimethyl-formamide

copper(l) iodide; caesium carbonate in methanol T=60°C; Ullmann condensation; 18 h; Inert atmosphere;

1: 79 percent / NaH, 1,3-dimethylimidazolium iodide / tetrahydrofuran / 5 h / Heating 2: 71 percent / methanol / 1.67 h / Heating 3: 88 percent / diethyl ether; tetrahydrofuran / 1 h / Ambient temperature 4: 86 percent / KCN / dimethylformamide / 1 h / 80 °C View Scheme

1: 71 percent / methanol / 1.67 h / Heating 2: 88 percent / diethyl ether; tetrahydrofuran / 1 h / Ambient temperature 3: 86 percent / KCN / dimethylformamide / 1 h / 80 °C View Scheme

1: 88 percent / diethyl ether; tetrahydrofuran / 1 h / Ambient temperature 2: 86 percent / KCN / dimethylformamide / 1 h / 80 °C View Scheme

暂无反应条件数据