3-[4-(苄氧基)苯基]-1-丙醇合成路线 （共 33 条）
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran T=-78 - 20°C; 2: With hydrogenchloride in tetrahydrofuran; water T=20°C; pH=2;
参考文献
CRYSTAX PHARMACEUTICALS, S.L.; AYMAMI BOFARULL, Juan; MARTINELL PEDEMONTE, Marc; CASTRO-PALOMINO LARIA, Julio; NICOLAS CHEVALIER, Franck Camille; VALLS VIDAL, Nuria
Patent: WO2010/70076 A1, 2010 ;
Location in patent: Page/Page column 105 ;
反应条件
sodium hydride in N,N-dimethyl-formamide 12 h; Heating;
参考文献
Boulard, Lucie; Bouzbouz, Samir; Cossy, Janine; Franck, Xavier; Figadere, Bruno
Tetrahedron Letters, 2004 , vol. 45, # 35 p. 6603 - 6605
反应条件
lithium aluminium tetrahydride in diethyl ether
参考文献
Guedin-Vuong, Denis; Nakatani, Yoichi
Bulletin de la Societe Chimique de France, 1986 , # 2 p. 245 - 252
反应条件
lithium aluminium tetrahydride in diethyl ether Heating;
参考文献
Wasikiewicz; Rokicki; Kielkiewicz; Paulus; Boehmer
Monatshefte fur Chemie, 1997 , vol. 128, # 8-9 p. 863 - 879
反应条件
1: With lithium borohydride in tetrahydrofuran T=20°C; 36 h; Inert atmosphere; 2: With ammonium chloride in tetrahydrofuran Inert atmosphere;
参考文献
Das, Biswanath; Suneel, Kanaparthy; Satyalakshmi, Gandham; Kumar, Duddukuri Nandan
Tetrahedron Asymmetry, 2009 , vol. 20, # 13 p. 1536 - 1540
反应条件
lithium borohydride in diethyl ether; water T=0 - 20°C; 24 h;
参考文献
Reddy, Parigi Raghavendar; Sudhakar, Chithaluri; Kumar, Jayprakash Narayan; Das, Biswanath
Helvetica Chimica Acta, 2013 , vol. 96, # 2 p. 289 - 295
反应条件
lithium aluminium tetrahydride in tetrahydrofuran Reduction; 2 h; Heating;
参考文献
Louis, Simon N.; Nero, Tracy L.; Iakovidis, Dimitri; Colagrande, Felicia M.; Jackman, Graham P.; Louis, William J.
European Journal of Medicinal Chemistry, 1999 , vol. 34, # 11 p. 919 - 937
反应条件
1.1: NaH / dimethylformamide / 0.17 h / 0 °C 1.2: 72 percent / dimethylformamide / 20 °C 2.1: methanol / 16 h / 25 °C 3.1: 1.0 g / DIBAL-H / toluene / 0.75 h View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 50, # 14 p. 3359 - 3368
反应条件
potassium carbonate in ethanol 3 h; Heating;
参考文献
Boll, Per M.; Hald, Mogens; Parmar, Virinder S.; Tyagi, Om Dutt; Bisht, Kirpal S.; et al.
Phytochemistry (Elsevier), 1992 , vol. 31, # 3 p. 1035 - 1037
反应条件
hydrogenchloride in diethyl ether; ethyl acetate; N,N-dimethyl-formamide
参考文献
E. R. Squibb and Sons, Inc.
Patent: US5100889 A1, 1992 ;
