1: With 4-(N,N-dimethlyamino)pyridine; N-ethyl-N,N-diisopropylamine; p-toluenesulfonyl chloride in 1,2-dichloro-ethane T=20°C; 1 h; 2: With hydroxylamine hydrochloride; N-ethyl-N,N-diisopropylamine in 1,4-dioxane; water T=37°C; 120 h; Further stages.;

1: 84 percent / Ph3P, CCl4 / CH2Cl2 / 3 h / Heating 2: 97 percent / H2O / 2 h / 50 °C 3: 91 percent / aq. NH3 / 5 h / 50 °C View Scheme

pyridine T=50°C; 12 h;

o-nitrobenzenesulfonyl peroxy radical

pyridine