1: With sodium hydroxide in ethanol; water T=20°C; 4 h; Inert atmosphere; 2: With hydrogenchloride in water pH=3; Inert atmosphere;

2,6-di-tert-butyl-4-methyl-phenol; 4 A molecular sieve; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in N,N-dimethyl-formamide T=80°C; P=2660 Torr; 21 h;

1: methyl 2-iodobenzoate With diethylzinc in hexane; N,N-dimethyl-formamide T=20°C; 5 h; 2: allyl bromide in hexane; N,N-dimethyl-formamide T=20°C; 20 h; Further stages.;

pyridine; NiI2; tetrabutylammomium bromide; 4,4'-di-tert-butyl-2,2'-dipyridyl; magnesium chloride; zinc in N,N-dimethyl acetamide T=60°C; 12 h; Inert atmosphere;

LiCl; CO; dichloro{1,1'-bis(diphenylphosphino)ferrocene}palladium(II) in N,N-dimethyl-formamide the triflate and the stannane in DMF contg. the Pd catalyst and LiCl heated at 80°C under 1 atm CO for 21 h; cooled to room temp., dild. with ether, filtered, filtrate washed with water and satd. NaCl soln., dried, concd., chromd. (flash column, hexanes/EtOAc);

tetrakis(triphenylphosphine) palladium(0) in benzene T=100°C; 16 h;

cesium fluoride; tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran Suzuki-Miyaura cross-coupling; Heating;

tetrakis(triphenylphosphine) palladium(0) in N,N-dimethyl-formamide T=120°C; Stille coupling; 0.166667 h; Microwave irradiation;

bis-triphenylphosphine-palladium(II) chloride in tetrahydrofuran T=60°C; 12 h;

1: methyl 2-iodobenzoate With chloro-trimethyl-silane; zinc in tetrahydrofuran T=70°C; 24 h; 2: 3-chloroprop-1-ene With bis(dibenzylideneacetone)-palladium(0) in tetrahydrofuran T=0°C; 18 h;