hydrogenchloride T=60°C; 0.5 h;

1: acetone With 6'-hydroxy-9-amino-9-deoxy-epiquinidine; (S)-BINOL-phosphoric acid T=20°C; 0.166667 h; 2: (E)-3-methylpent-3-en-2-one; mercapto acetic acid ethylester T=40°C; sulfa Michael addition; 60 h; optical yield given as percent eestereoselective reaction;

sulfuric acid in benzene 6 h; Heatingvar. reagents; Product distribution;