n-butyllithium in tetrahydrofuran 18 h; Ambient temperature;

1: 87 percent / potassium carbonate / toluene / 1) reflux, 3 h, 2) room temperature, 16 h 2: 76 percent / n-butyllithium / tetrahydrofuran / 18 h / Ambient temperature View Scheme

1: 87 percent / potassium carbonate / toluene / 1) reflux, 3 h, 2) room temperature, 16 h 2: 76 percent / n-butyllithium / tetrahydrofuran / 18 h / Ambient temperature View Scheme