tetrabutyl ammonium fluoride in tetrahydrofuran T=0 - 20°C; Inert atmosphere;

potassium carbonate in N,N-dimethyl-formamide 6 h;

1.1: potassium tert-butylate / tetrahydrofuran / 5 h / 0 °C / Inert atmosphere 2.1: n-butyllithium / tetrahydrofuran; hexane / 2 h / 0 °C / Inert atmosphere 2.2: 0 - 20 °C / Inert atmosphere 3.1: hydrogenchloride; water / methanol / 10 h / 20 °C / Inert atmosphere 4.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0 - 20 °C / Inert atmosphere View Scheme

1.1: n-butyllithium / tetrahydrofuran; hexane / 2 h / 0 °C / Inert atmosphere 1.2: 0 - 20 °C / Inert atmosphere 2.1: hydrogenchloride; water / methanol / 10 h / 20 °C / Inert atmosphere 3.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0 - 20 °C / Inert atmosphere View Scheme

1.1: potassium tert-butylate / tetrahydrofuran / 5 h / 0 °C / Inert atmosphere 2.1: n-butyllithium / tetrahydrofuran; hexane / 2 h / 0 °C / Inert atmosphere 2.2: 0 - 20 °C / Inert atmosphere 3.1: hydrogenchloride; water / methanol / 10 h / 20 °C / Inert atmosphere 4.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0 - 20 °C / Inert atmosphere View Scheme

1.1: n-butyllithium / tetrahydrofuran; hexane / 2 h / 0 °C / Inert atmosphere 1.2: 0 - 20 °C / Inert atmosphere 2.1: hydrogenchloride; water / methanol / 10 h / 20 °C / Inert atmosphere 3.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0 - 20 °C / Inert atmosphere View Scheme

1: potassium hexamethylsilazane / tetrahydrofuran; toluene / 3 h / |Inert atmosphere 2: toluene-4-sulfonic acid / 24 h / |Inert atmosphere View Scheme