(E)-3-甲基戊-2-烯-4-炔-1-醇合成路线 （共 30 条）
反应条件
1: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; pyrrolidine / tetrahydrofuran / 6 h / |Inert atmosphere; |Darkness 2: [RhCl(η2:η2-cycloocta-1,5-diene)]2 / dichloromethane / 6 h / 20 °C / |Inert atmosphere 3: tetrabutyl ammonium fluoride / tetrahydrofuran / 3 h / 20 °C 4: manganese(IV) oxide; sodium carbonate / dichloromethane / 4 h / |Inert atmosphere View Scheme
参考文献
Bergueiro, Julian; Montenegro, Javier; Saa, Carlos; Lopez, Susana
Chemistry - A European Journal, 2012 , vol. 18, # 44 p. 14100 - 14107
反应条件
hydrogen; palladium T=390°C; isotopic kinetic effect; Product distribution;
参考文献
Karavanov, A. N.; Gryaznov, V. M.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1988 , vol. 37, p. 2223 - 2227
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1988 , # 11 p. 2469 - 2473
反应条件
hydrogen; nickel different catalysts (group VIII);
参考文献
Sokolo'skii, D. V.; Zhubanova, L. K.; Omarkulov, T. O.; Sadykov, U. A.; Korolev, A. V.
Russian Journal of Physical Chemistry, 1990 , vol. 64, # 1 p. 43 - 46
Zhurnal Fizicheskoi Khimii, 1990 , vol. 64, # 1 p. 83 - 87
反应条件
toluene-4-sulfonic acid 1.) 5 deg C, 2.) RT, 10 min;
参考文献
Rosenberger; McDougal; Bahr
Journal of Organic Chemistry, 1982 , vol. 47, # 11 p. 2130 - 2134
反应条件
ammonium hydroxide; n-Bu3SnH; CuCN
参考文献
Galderma Research and Development
Patent: US6180674 B2, 2001 ;
反应条件
1.1: tris(1,3-divinyl-1,1,3,3-tetramethyldisiloxane)-bis-platinum(0); tri-tert-butyl phosphine / tetrahydrofuran; anhydrous xylene / 0.5 h / |Inert atmosphere 1.2: |Inert atmosphere 2.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.5 h / 20 °C / |Inert atmosphere; |Darkness 2.2: 1 h / |Inert atmosphere; |Darkness 3.1: manganese(IV) oxide; sodium carbonate / dichloromethane / 4 h / |Inert atmosphere View Scheme
参考文献
Bergueiro, Julian; Montenegro, Javier; Saa, Carlos; Lopez, Susana
Chemistry - A European Journal, 2012 , vol. 18, # 44 p. 14100 - 14107
反应条件
1: palladium; CaCO3; methyl acetate 2: aluminium tert-butylate; benzene View Scheme
参考文献
Cheeseman et al.
Journal of the Chemical Society, 1949 , p. 2034
反应条件
1: 83 percent / Ph3P, diethyl azodicarboxylate / tetrahydrofuran / 16 h 2: 55 percent / Et3N, copper(I) iodide / (Ph3P)2PdCl2 / CH2Cl2 / 6 h 3: 98 percent / CH2Cl2 / 16 h 4: 22 percent / oxalic acid / tetrahydrofuran; H2O / 0.75 h View Scheme
参考文献
Tabrizi, M. Aghazade; Baraldi; Guarneri; Manfredini; Pollini; Simoni
Tetrahedron Letters, 1991 , vol. 32, # 5 p. 683 - 686
反应条件
hydrogen; palladium T=390°C; isotopic kinetic effect; Product distribution;
参考文献
Karavanov, A. N.; Gryaznov, V. M.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1988 , vol. 37, p. 2223 - 2227
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1988 , # 11 p. 2469 - 2473
反应条件
n-butyllithium 1.) THF, hexane, 0 deg C, 1 h, 2.) THF, hexane, r.t., overnight; Yield givenMultistep reaction;
参考文献
Betzer, Jean-Francois; Pancrazi, Ange
Synthesis, 1999 , # 4 p. 629 - 634
