4-(N,N-dimethlyamino)pyridine; triethylamine in tetrahydrofuran 1.) 0 deg C, 30 min; 2.) room temp., 2.5 h;

1: sulfuric acid; water; mercury(II) oxide / 1.33 h / 60 °C 2: triethylamine / dichloromethane / 16 h / 25 °C / Inert atmosphere 3: titanium tetrachloride / dichloromethane / 18 h / -25 - -20 °C / Inert atmosphere 4: benzene-selenenyl bromide; sodium hydrogencarbonate / methanol; dichloromethane / 3 h / 25 °C / Inert atmosphere 5: tetrabutyl ammonium fluoride / tetrahydrofuran / 16 h / 25 °C / Inert atmosphere View Scheme

1: 1) H2, quinoline, 2) Et3N, 4-dimethylaminopyridine / 1) Lindlar's catalyst / 1) methanol, 5 p.s.i., 2) CH2Cl2, RT, 2 h 2: 84 percent / phenylisocyanate, Et3N / benzene / Ambient temperature 3: 96 percent / Li2O*H2O / methanol; H2O / 0.17 h / 0 °C 4: 68 percent / diethyldiazocarboxylate, PPh3 / tetrahydrofuran / 24 h / Ambient temperature 5: 41 percent / Mo(CO)6 / acetonitrile; H2O / 2 h / Heating 6: 48 percent / p-TsOH / methanol; various solvent(s) / 1 h / Ambient temperature View Scheme

1: 77 percent / H2 / Lindlar catalyst / ethanol 2: 62 percent / CBr4; PPh3 / CH2Cl2 / 3 h / 20 °C View Scheme

pyridinium p-toluenesulfonate in dichloromethane 2 h; Ambient temperature;

暂无反应条件数据

暂无反应条件数据

1: (i) EtMgBr, (ii) /BRN= 969467/, (iii) aq. H2SO4 2: H2, quinoline / Lindlar catalyst / toluene View Scheme

hydrogen; palladium T=390°C; isotopic kinetic effect; Product distribution;

benzophenone in acetonitrile 0.333333 - 4 h; UV-irradiationMicrowave irradiation; Product distribution / selectivity;