potassium carbonate in water; N,N-dimethyl-formamide

1: 90 percent / K2CO3 / dimethylformamide / 5.5 h / 100 °C 2: 1.) pyrrolidine, 2.) Raney nickel, hydrazine hydrate / 1) DMF, 110 deg C, 3.5 h; 2) water, THF, CH3OH, rt --> 43 deg C View Scheme

1: 90 percent / K2CO3 / dimethylformamide / 5.5 h / 100 °C 2: 1.) pyrrolidine, 2.) Raney nickel, hydrazine hydrate / 1) DMF, 110 deg C, 3.5 h; 2) water, THF, CH3OH, rt --> 43 deg C View Scheme

pyrrolidine; nickel; hydrazine hydrate 1) DMF, 110 deg C, 3.5 h; 2) water, THF, CH3OH, rt --> 43 deg C; Yield given. Multistep reaction;