甲基-2 -(4-异丁基苯基)丙酸合成路线 (共 47 条)
参考文献
Tetrahedron Letters, , vol. 27, # 34 p. 3995 - 3998
反应条件
methanol; Na-SG in tetrahydrofuran T=0 - 25°C; Bouveault-Blanc reduction; Inert atmosphere;
参考文献
Bodnar, Brian S.; Vogt, Paul F.
Journal of Organic Chemistry, 2009 , vol. 74, # 6 p. 2598 - 2600
反应条件
Thermotoga maritima esterase Tm1160 in aq. acetate buffer T=70°C; pH=5.5; Enzymatic reaction; enantioselective reaction;
参考文献
Wei, Tao; Feng, Shengxue; Mao, Duobin; Yu, Xuan; Du, Congcong; Wang, Xihua
Journal of Molecular Catalysis B: Enzymatic, 2013 , vol. 85-86, p. 23 - 30
反应条件
sodium hydroxide in water 11 h; Ambient temperaturehorse liver esterase, pH 7.2; Yield given. Yields of byproduct given;
参考文献
Ahmar, M.; Girard, C.; Bloch, R.
Tetrahedron Letters, 1989 , vol. 30, # 50 p. 7053 - 7056
反应条件
Novozym 435; water in tert-butyl methyl ether T=45°C; Kinetics; SolventConcentration; optical yield given as percent ee;
参考文献
Wang, Pei-Yun; Chen, Ying-Ju; Wu, An-Chi; Lin, Yi-Sheng; Kao, Min-Fang; Chen, Jin-Ru; Ciou, Jyun-Fen; Tsai, Shau-Wei
Advanced Synthesis and Catalysis, 2009 , vol. 351, # 14-15 p. 2333 - 2341
反应条件
1: With dimethyl sulfoxide; Candida rugosa lipase T=40°C; pH=9.8; 144 h; aq. buffer; 2: With hydrogenchloride in water pH=5; optical yield given as percent eeenantioselective reaction;
参考文献
Chavez-Flores, David; Salvador, James M.
Tetrahedron Asymmetry, 2012 , vol. 23, # 3-4 p. 237 - 239
反应条件
Thermotoga maritima esterase Tm1160 in aq. acetate buffer T=70°C; pH=5.5; Enzymatic reaction; enantioselective reaction;
参考文献
Wei, Tao; Feng, Shengxue; Mao, Duobin; Yu, Xuan; Du, Congcong; Wang, Xihua
Journal of Molecular Catalysis B: Enzymatic, 2013 , vol. 85-86, p. 23 - 30
反应条件
Trichosporon beigelli esterase in phosphate buffer T=29°C; pH=8.0; 96 h;
参考文献
Koul, Surrinder; Koul, Jawahir Lal; Singh, Budh; Kapoor, Munish; Parshad, Rajinder; Manhas, Kuldeep S.; Taneja, Subhash C.; Qazi, Ghulam N.
Tetrahedron Asymmetry, 2005 , vol. 16, # 15 p. 2575 - 2591
反应条件
sodium hydroxide in water 11 h; Ambient temperaturehorse liver esterase, pH 7.2; Yield given. Yields of byproduct given;
参考文献
Ahmar, M.; Girard, C.; Bloch, R.
Tetrahedron Letters, 1989 , vol. 30, # 50 p. 7053 - 7056
反应条件
hydrazine hydrate in ethanol 4 h; Heating;
参考文献
Sharma, Vibha; Khan
Pharmazie, 2003 , vol. 58, # 2 p. 99 - 103