反应条件
1: 84 percent / conc. H2SO4 / 1.5 h / 120 °C
2: 71 percent / POCl3 / 2 h / Heating
3: 87 percent / methanol / 48 h / Heating
4: 1) n-BuLi / 1) THF, hexane, -78 deg C, 5 min, 2) to -20 deg C
5: 46 percent / NaOMe / dimethylsulfoxide / 2 h / 90 - 95 °C
6: 14 percent / NaOMe / ethanol / Heating
View Scheme
参考文献
Davis, Steven E.; Rauckman, Barbara S.; Chan, Joseph H.; Roth, Barbara
Journal of Medicinal Chemistry, 1989 , vol. 32, # 8 p. 1936 - 1942
