4-苯甲酰基-苯甲酸甲酯合成路线 （共 24 条）
反应条件
bis(η3-allyl-μ-chloropalladium(II)) in N,N,N',N',N'',N''-hexamethylphosphoric triamide
T=20°C; 8 h;
参考文献
Bumagin, N. A.; Bumagina, I. G.; Kashin, A. N.; Beletskaya, I. P.
Doklady Chemistry, 1981 , vol. 261, p. 532 - 535
Dokl. Akad. Nauk SSSR Ser. Khim., 1981 , vol. 261, # 5 p. 1141 - 1144
反应条件
potassium fluoride; 18-crown-6 ether; 3-(2,4,6-trimethyl-phenyl)-5,6,7,8-tetrahydro-4H-cycloheptathiazol-3-ium perchlorate; potassium tert-butylate in tetrahydrofuran
T=25°C; 4 h; Inert atmosphere;
参考文献
Biju, Akkattu T.; Glorius, Frank
Angewandte Chemie - International Edition, 2010 , vol. 49, # 50 p. 9761 - 9764
反应条件
1: iodobenzene With chloro-trimethyl-silane; ethylene dibromide; zinc in tetrahydrofuran
2: 4-ethylsulfanylcarbonyl-benzoic acid methyl ester With bis(acetylacetonate)nickel(II) in tetrahydrofuran; toluene
T=20°C; 20 h;
参考文献
Shimizu, Toshiaki; Seki, Masahiko
Tetrahedron Letters, 2002 , vol. 43, # 6 p. 1039 - 1042
反应条件
tetrakis(triphenylphosphine) palladium(0) in 1-methyl-pyrrolidin-2-one
T=60°C; 6 h;
参考文献
Qin, Weiwei; Yasuike, Shuji; Kakusawa, Naoki; Kurita, Jyoji
Journal of Organometallic Chemistry, 2008 , vol. 693, # 17 p. 2949 - 2953
反应条件
1: 90 percent / Pd(OAc)2; PPh3 / dioxane / 10 h / 50 °C
View Scheme
参考文献
Tatamidani, Hiroto; Kakiuchi, Fumitoshi; Chatani, Naoto
Organic Letters, 2004 , vol. 6, # 20 p. 3597 - 3599
反应条件
carbon tetrabromide; oxygen
24 h; Irradiation;
参考文献
Hirashima, Shin-Ichi; Nobuta, Tomoya; Tada, Norihiro; Miura, Tsuyoshi; Itoh, Akichika
Organic Letters, 2010 , vol. 12, # 16 p. 3645 - 3647
反应条件
1: diethyl ether
2: 61 percent / KF / (η-C3H5PdCl)2 / 1,2-dimethoxy-ethane / 5 h / 100 °C
View Scheme
参考文献
Hatanaka, Yasuo; Fukushima, Satoshi; Hiyama, Tamejiro
Tetrahedron, 1992 , vol. 48, # 11 p. 2113 - 2126
反应条件
thionyl chloride
nachf. Einw. von Methanol;
参考文献
Smith
Journal of the American Chemical Society, 1921 , vol. 43, p. 1920
反应条件
trifluorormethanesulfonic acid
T=85°C; Friedel-Crafts acylation; 8 h;
参考文献
Hwang, Je Pil; Surya Prakash; Olah, George A.
Tetrahedron, 2000 , vol. 56, # 37 p. 7199 - 7203
反应条件
1: aluminium chloride / Verseifung des entstandenen Methylesters mit alkoh. Kalilauge
2: thionyl chloride / nachf. Einw. von Methanol
View Scheme
参考文献
Smith
Journal of the American Chemical Society, 1921 , vol. 43, p. 1920
