2-氯-1-(4-氟苯基)乙醇合成路线 （共 8 条）
反应条件
Pseudomonas sp. lipase in toluene T=60°C; 5 h; Enzymatic reaction; Title compound not separated from byproducts.;
参考文献
Journal of Organic Chemistry, , vol. 67, # 25 p. 9006 - 9010
反应条件
in diethyl ether 48 h; Ambient temperatureamano lipase P from Pseudomonas sp.;
参考文献
Tetrahedron Asymmetry, , vol. 2, # 2 p. 113 - 122
参考文献
Tetrahedron Asymmetry, , vol. 2, # 2 p. 113 - 122
反应条件
2: lithium aluminum hydride / tetrahydrofuran / 1 h / Ambient temperature View Scheme
参考文献
Nieduzak; Margolin
Tetrahedron Asymmetry, 1991 , vol. 2, # 2 p. 113 - 122
反应条件
2: lithium aluminum hydride / tetrahydrofuran / 1 h / Ambient temperature View Scheme
参考文献
Nieduzak; Margolin
Tetrahedron Asymmetry, 1991 , vol. 2, # 2 p. 113 - 122
反应条件
1: chloromethyl iodide With isopropylmagnesium chloride lithium chloride complex in tetrahydrofuran
T=-78°C; 0.166667 h; Inert atmosphere;
2: 4-fluorobenzaldehyde in tetrahydrofuran
T=-78°C; 0.5 h; Inert atmosphere;
参考文献
Nishimura, Rodolfo H.V.; Toledo, Fabiano T.; Lopes, Joao L.C.; Clososki, Giuliano C.
Tetrahedron Letters, 2013 , vol. 54, # 4 p. 287 - 290
反应条件
sodium tetrahydroborate in methanol
T=0 - 20°C;
参考文献
Traeft, Annika; Bogar, Krisztian; Warner, Madeleine; Baeckvall, Jan-E.
Organic Letters, 2008 , vol. 10, # 21 p. 4807 - 4810
反应条件
N-chloro-succinimide; thiourea in tetrahydrofuran; water
T=23°C; 2 h;
参考文献
Bentley, Paul A.; Mei, Yujiang; Du, Juan
Tetrahedron Letters, 2008 , vol. 49, # 8 p. 1425 - 1427
