1: 2-(3-chlorophenoxy)ethanol With n-butyllithium; Mg(OCH2CH2OEt)2 in tetrahydrofuran T=-78°C; deprotonation; 0.25 h; 2: With Li-naphthalenide in tetrahydrofuran T=-78 - -50°C; lithium-halogen exchange; 0.333333 h; 3: carbon dioxide in tetrahydrofuran; diethyl ether Carboxylation;

sodium hydroxide in ethanol

potassium carbonate; copper dichloride T=130°C; 20 h; Inert atmosphereSchlenk technique;

lithium aluminium tetrahydride

2: PCl5 / 130 - 135 °C / Hydrolyse des Reaktionsprodukts View Scheme

1: aqueous KOH / 100 °C / 3-std. Erwaermen 3: PCl5 / 130 - 135 °C / Hydrolyse des Reaktionsprodukts View Scheme

ethanol; sodium ethanolate

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