ruthenium(II)-carbonyl-tris(triphenylphosphine) dihydride; perfluorooctylcarboxylic acid; 1,4-di(diphenylphosphino)-butane in acetone T=100°C; 40 h; Inert atmosphere; optical yield given as percent dediastereoselective reaction;

ruthenium(II)-carbonyl-tris(triphenylphosphine) dihydride; perfluorooctylcarboxylic acid; 1,4-di(diphenylphosphino)-butane in isopropyl alcohol; acetone T=100°C; 40 h; Inert atmosphere; optical yield given as percent dediastereoselective reaction;

(i) Mg, FeCl3, EtBr, THF, (ii) /BRN= 505984/; Multistep reaction;