3-(4-甲氧基苯基)-3,4-二氢萘-1(2H)-酮合成路线 （共 13 条）
反应条件
hydrogen bromide; acetic acid
6 h; Heating;
参考文献
Jung, Jae-Chul; Lee, Ji-Ho; Oh, Seikwan; Lee, Jae-Gon; Park, Oee-Sook
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 22 p. 5527 - 5531
参考文献
Jung, Jae-Chul; Lee, Ji-Ho; Oh, Seikwan; Lee, Jae-Gon; Park, Oee-Sook
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 22 p. 5527 - 5531
反应条件
1: 75 percent / aq.H2SO4 / 8 h / Heating
2: 60 percent / polyphosphoric acid (PPA) / 1 h / Heating
View Scheme
参考文献
Selvaraj, S.; Rajendran, A. S.; Arumugam, N.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1987 , vol. 26, # 1-12 p. 1047 - 1049
反应条件
1: 97 percent / Zn; I2 / benzene / 1 h / Heating
2: 90 percent / Et3SiH; TFA; BF3*Et2O / CH2Cl2 / 8 h / Heating
3: 92 percent / aq. KOH / 8 h / Heating
4: 85 percent / polyphosphoric acid / 1 h / 80 °C
View Scheme
参考文献
Jung, Jae-Chul; Lee, Ji-Ho; Oh, Seikwan; Lee, Jae-Gon; Park, Oee-Sook
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 22 p. 5527 - 5531
反应条件
1: 89 percent / AlCl3 / CH2Cl2 / 16 h / -10 °C
2: 97 percent / Zn; I2 / benzene / 1 h / Heating
3: 90 percent / Et3SiH; TFA; BF3*Et2O / CH2Cl2 / 8 h / Heating
4: 92 percent / aq. KOH / 8 h / Heating
5: 85 percent / polyphosphoric acid / 1 h / 80 °C
View Scheme
参考文献
Jung, Jae-Chul; Lee, Ji-Ho; Oh, Seikwan; Lee, Jae-Gon; Park, Oee-Sook
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 22 p. 5527 - 5531
反应条件
1: 89 percent / AlCl3 / CH2Cl2 / 16 h / -10 °C
2: 97 percent / Zn; I2 / benzene / 1 h / Heating
3: 90 percent / Et3SiH; TFA; BF3*Et2O / CH2Cl2 / 8 h / Heating
4: 92 percent / aq. KOH / 8 h / Heating
5: 85 percent / polyphosphoric acid / 1 h / 80 °C
View Scheme
参考文献
Jung, Jae-Chul; Lee, Ji-Ho; Oh, Seikwan; Lee, Jae-Gon; Park, Oee-Sook
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 22 p. 5527 - 5531
反应条件
1: 90 percent / Et3SiH; TFA; BF3*Et2O / CH2Cl2 / 8 h / Heating
2: 92 percent / aq. KOH / 8 h / Heating
3: 85 percent / polyphosphoric acid / 1 h / 80 °C
View Scheme
参考文献
Jung, Jae-Chul; Lee, Ji-Ho; Oh, Seikwan; Lee, Jae-Gon; Park, Oee-Sook
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 22 p. 5527 - 5531
反应条件
1.1: potassium hydroxide / water / 3 h / Reflux
2.1: sulfuric acid / water / 8 h / Reflux
2.2: polyphosphoric acid / 1 h / 80 °C
View Scheme
参考文献
Jung, Jae-Chul; Jang, Soyong; Oh, Seikwan; Park, Oee-Sook
Journal of Chemical Sciences, 2010 , vol. 122, # 6 p. 833 - 838
反应条件
1.1: copper(l) chloride / tetrahydrofuran / 1 h / 0 °C
2.1: potassium hydroxide / water / 3 h / Reflux
3.1: sulfuric acid / water / 8 h / Reflux
3.2: polyphosphoric acid / 1 h / 80 °C
View Scheme
参考文献
Jung, Jae-Chul; Jang, Soyong; Oh, Seikwan; Park, Oee-Sook
Journal of Chemical Sciences, 2010 , vol. 122, # 6 p. 833 - 838
反应条件
1.1: pyrrolidine; acetic acid / toluene / 3 h / Reflux
2.1: copper(l) chloride / tetrahydrofuran / 1 h / 0 °C
3.1: potassium hydroxide / water / 3 h / Reflux
4.1: sulfuric acid / water / 8 h / Reflux
4.2: polyphosphoric acid / 1 h / 80 °C
View Scheme
参考文献
Jung, Jae-Chul; Jang, Soyong; Oh, Seikwan; Park, Oee-Sook
Journal of Chemical Sciences, 2010 , vol. 122, # 6 p. 833 - 838
