ARENA PHARMACEUTICALS, INC.; JONES, Robert M.; BUZARD, Daniel J.; GHARBAOUI, Tawfik; JOHNSON, Benjamin R.; KASEM, Michelle; SCHRADER, Thomas O.; STIRN, Scott
Patent: WO2011/109471 A1, 2011 ;
Location in patent: Page/Page column 118-119 ;
WO 2011/109471 A1
sulfuric acid; dihydrogen peroxide; iron(II) sulfate in dichloromethane; water T=-10 - 0°C; 0.25 h; Variation of mole ratio of the base and the peroxide.; Product distribution;
参考文献
Heinisch, Gottfried; Loetsch, Gerhard
Tetrahedron, 1986 , vol. 42, # 21 p. 5973 - 5977