1: 1-chloro-4-iodobenzene With tris-(dibenzylideneacetone)dipalladium(0); (1-Ad)2P(O)H in tetrahydrofuran Kumada-Corriu coupling reaction; 0.0833333 h; Inert atmosphere; 2: (6-methyl-2-pyridyl)magnesium bromide in tetrahydrofuran T=60°C; Kumada-Corriu coupling reaction; 20 h; Inert atmosphere; chemoselective reaction;

1: 1-chloro-4-bromobenzene With tris-(dibenzylideneacetone)dipalladium(0); (1-Ad)2P(O)H in tetrahydrofuran Kumada-Corriu coupling reaction; 0.0833333 h; Inert atmosphere; 2: (6-methyl-2-pyridyl)magnesium bromide in tetrahydrofuran T=60°C; Kumada-Corriu coupling reaction; 20 h; Inert atmosphere; chemoselective reaction;

1: benzene 2: ethanolic NaOH-solution; soda lime / 380 °C / unter vermindertem Druck View Scheme