2-叠氮-6-苄基氨基嘌呤合成路线 （共 8 条）
反应条件
hydrogenchloride; acetic acid; sodium nitrite in water
T=20°C; 96 h; Darkness;
参考文献
Steklov, Mikhail Yu.; Tararov, Vitali I.; Romanov, Georgy A.; Mikhailov, Sergey N.
Nucleosides, Nucleotides and Nucleic Acids, 2011 , vol. 30, # 7-8 p. 503 - 511
反应条件
1: water / 4.5 h / 70 °C
2: water; sodium hydroxide / 3 h / 20 °C
3: hydrogenchloride; zinc(II) chloride; sodium nitrite / water / 1 h / -5 - 5 °C
4: isopropyl alcohol / 3.5 h / 82 °C
5: hydrazine hydrate / water / 1.5 h / Reflux
6: hydrogenchloride; acetic acid; sodium nitrite / water / 96 h / 20 °C / Darkness
View Scheme
参考文献
Steklov, Mikhail Yu.; Tararov, Vitali I.; Romanov, Georgy A.; Mikhailov, Sergey N.
Nucleosides, Nucleotides and Nucleic Acids, 2011 , vol. 30, # 7-8 p. 503 - 511
反应条件
1: water; sodium hydroxide / 3 h / 20 °C
2: hydrogenchloride; zinc(II) chloride; sodium nitrite / water / 1 h / -5 - 5 °C
3: isopropyl alcohol / 3.5 h / 82 °C
4: hydrazine hydrate / water / 1.5 h / Reflux
5: hydrogenchloride; acetic acid; sodium nitrite / water / 96 h / 20 °C / Darkness
View Scheme
参考文献
Steklov, Mikhail Yu.; Tararov, Vitali I.; Romanov, Georgy A.; Mikhailov, Sergey N.
Nucleosides, Nucleotides and Nucleic Acids, 2011 , vol. 30, # 7-8 p. 503 - 511
反应条件
1: trichlorophosphate / 1,2-dichloro-ethane / 8 h / 80 °C
2: water / 4.5 h / 70 °C
3: water; sodium hydroxide / 3 h / 20 °C
4: hydrogenchloride; zinc(II) chloride; sodium nitrite / water / 1 h / -5 - 5 °C
5: isopropyl alcohol / 3.5 h / 82 °C
6: hydrazine hydrate / water / 1.5 h / Reflux
7: hydrogenchloride; acetic acid; sodium nitrite / water / 96 h / 20 °C / Darkness
View Scheme
参考文献
Steklov, Mikhail Yu.; Tararov, Vitali I.; Romanov, Georgy A.; Mikhailov, Sergey N.
Nucleosides, Nucleotides and Nucleic Acids, 2011 , vol. 30, # 7-8 p. 503 - 511
反应条件
1: hydrazine hydrate / water / 1.5 h / Reflux
2: hydrogenchloride; acetic acid; sodium nitrite / water / 96 h / 20 °C / Darkness
View Scheme
参考文献
Steklov, Mikhail Yu.; Tararov, Vitali I.; Romanov, Georgy A.; Mikhailov, Sergey N.
Nucleosides, Nucleotides and Nucleic Acids, 2011 , vol. 30, # 7-8 p. 503 - 511
反应条件
1: hydrogenchloride; zinc(II) chloride; sodium nitrite / water / 1 h / -5 - 5 °C
2: isopropyl alcohol / 3.5 h / 82 °C
3: hydrazine hydrate / water / 1.5 h / Reflux
4: hydrogenchloride; acetic acid; sodium nitrite / water / 96 h / 20 °C / Darkness
View Scheme
参考文献
Steklov, Mikhail Yu.; Tararov, Vitali I.; Romanov, Georgy A.; Mikhailov, Sergey N.
Nucleosides, Nucleotides and Nucleic Acids, 2011 , vol. 30, # 7-8 p. 503 - 511
反应条件
1: isopropyl alcohol / 3.5 h / 82 °C
2: hydrazine hydrate / water / 1.5 h / Reflux
3: hydrogenchloride; acetic acid; sodium nitrite / water / 96 h / 20 °C / Darkness
View Scheme
参考文献
Steklov, Mikhail Yu.; Tararov, Vitali I.; Romanov, Georgy A.; Mikhailov, Sergey N.
Nucleosides, Nucleotides and Nucleic Acids, 2011 , vol. 30, # 7-8 p. 503 - 511
反应条件
1: isopropyl alcohol / 3.5 h / 82 °C
2: hydrazine hydrate / water / 1.5 h / Reflux
3: hydrogenchloride; acetic acid; sodium nitrite / water / 96 h / 20 °C / Darkness
View Scheme
参考文献
Steklov, Mikhail Yu.; Tararov, Vitali I.; Romanov, Georgy A.; Mikhailov, Sergey N.
Nucleosides, Nucleotides and Nucleic Acids, 2011 , vol. 30, # 7-8 p. 503 - 511
