5-甲氧基-1-[4-(三氟甲基)苯基]-1-戊酮合成路线 (共 2 条)
反应条件
magnesium in tetrahydrofuran
参考文献
Sun Pharmaceutical Industries Ltd.
Patent: US6380436 B1, 2002 ;
反应条件
1: in toluene T=-8 - 1°C; 8 - 10 h; 2: With hydrogenchloride; water T=40 - 45°C; pH=1 - 2; Product distribution / selectivity;
参考文献
WO2006/2691 A1, ;
Page/Page column 11-12 ;